>>333272The characters are definitely a lot more memorable in New Vegas. I can remember like one character from 3 making an impression on me, and that's John Henry Eden (who is basically a gag character). The core villain of the game is a guy called General Autumn, I guess. I could tell you absolutely nothing about that character, other than he was there at the end, and I shot him.
New Vegas has Mr House, Caeser, Benny, all of the companion characters are pretty good.